Needle free Drug Delivery Market Size Worth over USD 5,000 Million in 2035 | Roots Analysis
In recent years, the pharmaceutical industry has witnessed technological advancements with the emergence of the latest drug delivery devices, such as needle free systems, jet injectors, pen injectors and microneedle patches.

It is worth highlighting that these devices have in-built safety mechanisms (which minimize the risk of needlestick injuries) and include improvements in design, functionality and usability over conventional needles, thereby facilitating pain-free self-administration of vaccines and drugs across the dermis.
This has led towards a discernible shift in patient preferences towards painless drug administration, driving the increasing acceptance and adoption of these systems. Considering this shift, from conventional to user-friendly drug delivery alternatives, the global needle free drug delivery devices market is poised to witness substantial market growth during the forecast period.
The needle free drug delivery devices market is anticipated to be worth USD 2,720 million in 2024 and this value is likely to reach over USD 5,000 million by 2035, expanding at a CAGR of 5.8% according to a new report by Roots Analysis.
Key Report Takeaways
§ Currently over 45 players (established players as well as start-ups) claim to provide needle free injection systems; majority of these firms are based in North America.
§ Most of the needle free devices are disposable; of these, over 60% devices are used in the administration of biologics using spring-based actuators via subcutaneous route.
§ Currently over 70 microneedle devices are commercially available or under development; notably, around 70% of the commercialized microneedle devices were launched post-2000.
§ Microneedle device developers have attempted to cater to the needs of patients by developing a wide range of devices; 65% of the commercialized devices administer drugs in liquid form across diverse therapeutic areas.
§ In order to achieve a competitive edge, needle free injection system providers are presently focusing on the integration of advanced features into their respective needle free devices and affiliated offerings.
§ More than 60% of the hollow microneedle devices (peer group II) are commercially available; of these, 17% of the devices have the ability to target more than one therapeutic area.
§ An evaluation of both marketed / pipeline drugs reveals that several biologic candidates are likely to be considered for administration via subcutaneous route using these devices.
§ Majority (55%) of the market is anticipated to be captured by revenues generated from needle free injection system (NFIS), administering drugs via subcutaneous route; further, the market for vaccination is likely to grow at a faster pace.
§ The market opportunity associated with microneedle devices is likely to witness an annualized growth of 6.2% over the coming years; further, in the long term, insulin delivery segment is likely to drive growth of the market.
Competitive Landscape of Needle free Drug Delivery Devices Market
The needle free injection system market features nearly 50 large, mid-sized and small companies that are engaged in providing needle free injection systems / jet injectors. Currently, 91% of needle free injection systems are designed to administer liquid formulations. This can be attributed to the fact that liquid formulations increase the surface area of the drug, thereby enhancing its solubility and bioavailability. This allows for improved drug absorption and subsequent therapeutic effects. In addition, liquid needle jet injectors were one of the first variants to be developed. Notable examples of companies offering such devices include (in alphabetic order) Activa Brand Products, Aijex Pharma International, Akra Dermojet and American Medical Systems.
Regional Outlook
Majority of the microneedle device providers are headquartered in North America, followed by companies based in Europe. Currently, North America and Europe capture over 65% of the market share of the overall microneedle device market.
In recent years, demand for microneedle patches and systems have increased in North America, owing to the fact that administration of drugs using the microneedle device allows the drug molecules to enter directly into the epidermis. This allows more drug molecules to enter the skin, accelerating patient compliance and improved permeability and efficacy. However, in the coming years, Europe is likely to grow at a much faster rate as compared to other geographies.
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Key Players
Examples of key companies engaged in needle free drug delivery devices market (which have also been profiled in this market report; the complete list of companies is available in the full report) include:
§ 3M
§ Debiotech
§ INCYTO
§ Micropoint Technologies
§ NanoPass Technologies
§ Nemaura Pharma
§ Theraject
§ Antares Pharma
§ D’Antonio Consultants International
§ HNS International
§ Injex
§ INOVIO Pharmaceuticals
§ Medical International Technology
§ Mika Medical
§ Pharmajet
§ QS Medical Technology (Quinovare)
§ Zogenix
In April 2023, PharmaJet Partner Gennova Biopharmaceuticals submitted data for its needle-free mRNA-based Omicron specific Covid-19 booster shot for Emergency Use Authorization (EUA) to the office of the Drug Controller General of India (DCGI).
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Market Segments
Based on the research, Roots Analysis has segmented the Needle free Drug Delivery Devices Market into Type of Device (Needle Free Injection System and Microneedle Devices), Route of Administration, Actuation Mechanism, Product Usability, Application Area, Type of Load, Product Type, Type of Microneedle Device, Type of Material Used, Type of Intervention and Geography.
by Type of Device
§ Needle free Injection System
§ Microneedle Devices
by Route of Administration
§ Subcutaneous Route
§ Intramuscular Route
§ Intradermal Route
by Actuation Mechanism
§ Spring-based Devices
§ Compressed-gas Devices
§ Other Devices
by Product Usability
§ Reusable Devices
§ Disposable Devices
by Application Area
§ Insulin Delivery
§ Pain Management
§ Vaccination
§ Dermatology
§ Oncology
by Type of Load
§ Liquid-based Devices
§ Powder-based Devices
§ Projectile / Depot-based Devices
by Product Type
§ Fillable Devices
§ Prefilled Devices
by Type of Microneedle Device
§ Hollow Microneedles
§ Solid Microneedles
§ Dissolving Microneedles
§ Coated Microneedles
by Type of Material Used
§ Polymer Microneedles
§ Silicon Microneedles
§ Metal Microneedles
§ Ceramic Microneedles
by Type of Interventions
§ Vaccines
§ Therapeutic Agents
§ Other Interventions
by Geography
§ North America
§ Europe
§ Asia Pacific
§ Middle East and North Africa
§ Latin America
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